Author

Lee G. Fradkin

University of Massachusetts Chan Medical SchoolORCID 0000-0002-5282-2984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Ana BoulangeriD· 3 shared Jean‐Maurice DuraiD· 3 shared Claire MarquillyiD· 2 shared Germain U. BustoiD· 2 shared Bassem A. HassaniD· 1 shared Brittany S. LegeriD· 1 shared Camille Thinat· 1 shared Edward GinigeriD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Ana BoulangerORCID

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4 papers

Recent·Most cited

Non-autonomous Vnd acts with autonomous Appl during mushroom body axon growth in Drosophila

Claire Marquilly, Ana Boulanger, Germain U. Busto, Robert P. Zinzen, Bassem A. Hassan, Lee G. Fradkin, Jean‐Maurice Dura

This study shows that vnd is more critical than Appl for MB axon outgrowth, with vnd acting non-autonomously.

bioRxiv · Sep 1, 2023 · PreprintNeuroscience

HTT is a repressor of ABL activity required for APP induced axonal growth

Claire Marquilly, Germain U. Busto, Brittany S. Leger, Ana Boulanger, Edward Giniger, James A. Walker, Lee G. Fradkin, Jean‐Maurice Dura

The paper shows HTT represses ABL activity, which is necessary for axonal growth in Drosophila mushroom bodies.

PLoS Genetics · Jan 19, 2021Peer-reviewedNeuroscience

Axon-secreted chemokine-like Orion is a signal for astrocyte infiltration during neuronal remodeling

Ana Boulanger, Camille Thinat, Stephan L. Zuchner, Lee G. Fradkin, Hugues Lortat‐Jacob, Jean‐Maurice Dura

The paper identifies a new gene, orion, which is secreted by neurons and recruits astrocytes for axon pruning and debris removal during neuronal remodeling in Drosophila.

bioRxiv · Nov 23, 2020 · PreprintNeuroscience

Interplay between axonal Wnt5-Vang and dendritic Wnt5-Drl/Ryk signaling controls glomerular patterning in the Drosophila antennal lobe

Huey K. Hing, Jennifer Snyder, Noah Reger, Lee G. Fradkin

The paper shows that Wnt5 signaling through Vang and Drl/Ryk in Drosophila ORNs and PNs controls the rotation of DA1/VA1d glomeruli during antennal lobe development.

PLoS Genetics · May 1, 2020Peer-reviewedNeuroscience