Discovery of inhibitors of the Pseudomonas aeruginosa NADH:ubiquinone oxidoreductase (NQR) that hinder virulence factors
Sandaru M. Ileperuma, Jialin Li, Juilan Ortiz, Ty Shade, Camille Vasseur, Natascia A Ciancibello, Wael Elhenawy, Justin M. Di Trani
The paper identifies inhibitors of Pseudomonas aeruginosa NQR that affect virulence factors by disrupting electron transfer and proton pumping.
bioRxiv · Feb 27, 2026 · PreprintBiochemistry