Justin M. Di Trani

The paper identifies inhibitors of Pseudomonas aeruginosa NQR that affect virulence factors by disrupting electron transfer and proton pumping.

The paper uses cryo-EM to show that malate-quinone oxidoreductase associates with the CIII2CIV2 supercomplex in mycobacteria, linking Krebs cycle and respiration.

The paper determines the high-resolution structure of V-ATPase in native synaptic vesicles using cryo-EM, revealing interactions with cholesterol and synaptophysin.