Author

Wael Elhenawy

University of AlbertaORCID 0000-0002-4599-8500Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ahmed M. Soliman· 1 shared Bridgette HartleyiD· 1 shared Camille Vasseur· 1 shared David E. HeinrichsiD· 1 shared Elena I ArutyunovaiD· 1 shared Eytan WineiD· 1 shared Heather ArmstrongiD· 1 shared Howard S. YoungiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperMicrobiology

Ahmed M. Soliman

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Discovery of inhibitors of the Pseudomonas aeruginosa NADH:ubiquinone oxidoreductase (NQR) that hinder virulence factors

Sandaru M. Ileperuma, Jialin Li, Juilan Ortiz, Ty Shade, Camille Vasseur, Natascia A Ciancibello, Wael Elhenawy, Justin M. Di Trani

The paper identifies inhibitors of Pseudomonas aeruginosa NQR that affect virulence factors by disrupting electron transfer and proton pumping.

bioRxiv · Feb 27, 2026 · PreprintBiochemistry

Mechanistic insight into the regulation of virulence factor type 1 pili in pathogenic E. coli by rhomboid protease GlpG

Jimmy Lu, Elena I Arutyunova, Bridgette Hartley, Jonas Wong, Hyunjae Chung, Lanny Buchan, Heather Armstrong, Sadhna Phanse, Howard S. Young, Eytan Wine, Mohan Babu, Justin Chun, Wael Elhenawy, Olivier Julien, M. Joanne Lemieux

This study shows GlpG protease is essential for type 1 pili assembly in E. coli, affecting biofilm formation and bacterial fitness.

bioRxiv · Sep 9, 2025 · PreprintBiochemistry

Discovery of broad-spectrum bacterial polyamine detoxification inhibitors as potential antivirulence agents and antibiotic adjuvants

Peri B. Moulding, Ronald S. Flannagan, Jonas Wong, Olmo Martín-Cámara, Ahmed M. Soliman, Sonsoles Martín‐Santamaría, Wael Elhenawy, David E. Heinrichs, Omar M. El-Halfawy

bioRxiv · Oct 18, 2024 · PreprintMicrobiology