DLK inhibition has sex-specific effects on neuroprotection and locomotor recovery after spinal cord injury
John C. Aldrich, Samantha M. Alman, Sydney E. Lee, Ashley R. Scheinfeld, Canwen Zhang, Averi L. Pike, Fiona C. Bremner, Olivia Calderon, Sunil Goodwani, William J. Ray, Andrew D. Gaudet
This study shows that DLK inhibition after spinal cord injury improves neuroprotection in female mice but worsens recovery and increases lesion size in males.
Experimental Neurology · Feb 8, 2026Peer-reviewedNeuroscience