John C. Aldrich

DLK inhibition has sex-specific effects on neuroprotection and locomotor recovery after spinal cord injury

This study shows that DLK inhibition after spinal cord injury improves neuroprotection in female mice but worsens recovery and increases lesion size in males.

Spinal cord injury in rats disrupts thermoregulation and suppresses stress-induced hyperthermia

This study shows that spinal cord injury in rats disrupts stress-induced hyperthermia, which recovers over time.

Anxiety-like behaviors in mice unmasked: Revealing sex differences in anxiety using a novel light-heat conflict test

The paper introduces a novel TIDAL conflict test to assess sex differences in anxiety and heat sensitivity in mice, finding females exhibit stronger anxiety-like behaviors.

Genome-Wide Association Study and transcriptome analysis reveals a complex gene network that regulates opsin gene expression and cell fate determination in Drosophila R7 photoreceptor cells.

The paper identifies genetic factors influencing opsin expression and cell fate in Drosophila R7 photoreceptors through GWAS and transcriptome analysis.

Effects of dim light at night in C57BL6/J mice on recoveryafter spinal cord injury

This study examines the effects of dim light at night on recovery from spinal cord injury in mice, finding modest impacts on locomotion, pain, and mood-related behaviors.

Drosophila R8 photoreceptor cell subtype specification requires Notch and hibris.

This paper identifies hibris and Notch signaling as critical for specifying R8 photoreceptor cell subtypes in Drosophila, with hibris acting non-cell autonomously.

Identification of genes involved in the differentiation of R7y and R7p photoreceptor cells in Drosophila

The paper identifies genes involved in R7 photoreceptor cell differentiation in Drosophila through genetic screens and analyzes their effects on Rh3 expression.