Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections
Clemence Ngo, Camille Pierini-Malosse, Khalissa Rahmani, Michael Valente, Nils Collinet, Gilles Bessou, Capucine Guerry, Manon Fabregue, Solene Mathieu, Sarah Sharkaoui, Sophie Mazzoli, Amandine Sansoni, Frédéric FIORE, Caroline Laprie, Lena Alexopoulou, , Elena Tomasello
This study shows that plasmacytoid dendritic cells (pDCs) and their interferons are dispensable or harmful in systemic and respiratory viral infections in mice.
Nature Immunology · Sep 29, 2025Peer-reviewedImmunology