Bernard Malissen

This study shows that plasmacytoid dendritic cells (pDCs) and their interferons are dispensable or harmful in systemic and respiratory viral infections in mice.

This study shows that Xcr1+ cDC1 cells promote atherosclerosis progression, as their depletion reduces plaque formation and T cell activation in mice.

The study identifies Claudin 1 on DC1s as essential for their positioning near mTECs, facilitating antigen transfer and DC1 maturation, which maintains central tolerance.

This paper shows that BIN1 overexpression in mice leads to early structural and functional impairments in hippocampal pathways associated with Alzheimer's disease, independent of A-beta changes.