Author
Gladstone Institutes
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Poorvi H. Dua, Bazilco M.J. Simon, Chiara B.E. Marley…·Luke M. Judge
This paper demonstrates haplotype editing with CRISPR/Cas9 to target NEFL missense mutations in iPSC-derived motor neurons, showing therapeutic potential and challenges in disrupting mutant allele expression.
Carissa M. Feliciano, Kenneth Kun-yu Wu, Hannah L. Watry…·Luke M. Judge
This paper demonstrates allele-specific CRISPR gene editing in a human CMT2E model rescues disease pathology by inactivating the mutant NEFL allele.
Hannah L. Watry, Carissa M. Feliciano, Ketrin Gjoni…·Luke M. Judge
The paper introduces ddXR, a method to rapidly and accurately quantify DNA excisions and inversions without sequencing, revealing high rates of large excisions and low dependence on linear distance.