Antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase: pseudouridimycin
Sonia Ilaria Maffioli, Yu Zhang, David Degen, Thomas Carzaniga, Giancarlo Del Gatto, Stefania Serina, Paolo Monciardini, Carlo Mazzetti, Paola Guglierame, Gianpaolo Candiani, Alina Iulia Chiriac, Giuseppe Facchetti, Petra Kaltofen, Hans‐Georg Sahl, Gianni Dehò, , Richard H. Ebright
This paper discovers pseudouridimycin, a novel antibacterial compound that inhibits bacterial RNA polymerase and shows potent activity against drug-resistant pathogens.
Cell · Jun 1, 2017Peer-reviewedMolecular Biology