Author

Carmen Butan

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Chenou Zhang· 1 shared Dhasakumar S Navaratnam· 1 shared Dhasakumar S. NavaratnamiD· 1 shared Fred J Sigworth· 1 shared Graham P. RosemaniD· 1 shared Jie Yang· 1 shared Joseph Santos-Sacchi· 1 shared Joseph Santos‐SacchiiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperPhysiology

Chenou Zhang

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Author profile →

3 papers

Recent·Most cited

SCN- induces prestin contraction through reduced intermonomer angles and a modified transporter like movement of each monomer.

Richard Mariadasse, Molly Powers, Jun-Ping Bai, Chenou Zhang, Sneha Subramaniya, Jie Yang, Fred J Sigworth, Venkat Kalyana Sundaram, Carmen Butan, Oliver Beckstein, Joseph Santos-Sacchi, Dhasakumar S Navaratnam

The paper investigates how SCN- induces prestin contraction through structural changes in its dimers and monomers, associated with altered intermonomer angles and beta sheet loss.

bioRxiv · Nov 3, 2026 · PreprintPhysiology

Distinct Filament Conformation for Receptor-Bound Amyloid-β from Alzheimers Disease Brain

Mikhail A. Kostylev, Carmen Butan, Graham P. Roseman, Yangyi Liu, Tanina Arab, Ruibing Wu, Pallavi P. Gopal, Stephen M. Strittmatter

The paper identifies a distinct receptor-bound amyloid-β filament conformation in Alzheimer's disease brain that interacts with prion protein and causes synaptic damage.

Nature Communications · Jul 22, 2026Peer-reviewedNeuroscience

Single particle cryo-EM structure of the outer hair cell motor protein prestin

Carmen Butan, Qiang Song, Jun-Ping Bai, Winston J. T. Tan, Dhasakumar S. Navaratnam, Joseph Santos‐Sacchi

This paper presents the single particle cryo-EM structure of prestin from gerbil at 4.0 Å resolution, revealing its dimeric architecture and structural features that challenge the extrinsic voltage sensor hypothesis.

Nature Communications · Jan 12, 2022Peer-reviewedNeuroscience