Chromosomal instability and chromosome 17p loss drive convergentNDE1 synthetic lethality in metastatic cancer cells
Caroline Teddy, Jacob P. Hoj, Julia D. Caci, Min Lü, Shane T. Killarney, Tal Ben-Yishay, Uri Ben‐David, Kris C. Wood
The paper identifies NDE1 as a synthetic lethal target in metastatic cancer cells driven by chromosomal instability and Chr17p loss.
bioRxiv · Feb 12, 2026 · PreprintCancer Biology