Author

Tal Ben-Yishay

Tel Aviv UniversityORCID 0009-0005-1305-0001Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Approach:genetic perturbation / CRISPR· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Linoy Raz· 2 shared Uri Ben‐DavidiD· 2 shared Adi V Tarrab· 1 shared Amjad Zoabi· 1 shared Caroline Teddy· 1 shared Eli ReuveniiD· 1 shared Gil LeoriD· 1 shared Giovanni BlandinoiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Linoy Raz

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 30, 2026

Mapping chromothripsis across human cancer cell lines reveals genome evolution and therapeutic vulnerabilities

Gil Leor, Tal Ben-Yishay, Adi V Tarrab…·Uri Ben‐David

This study maps chromothripsis in 1,646 human cancer cell lines, showing its conservation with tumors, higher prevalence, and therapeutic vulnerabilities to HDAC inhibitors.

DOI 10.64898/2026.10.30.763015

humanwhole-genome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 8, 2026

Genomic fidelity and evolution of cancer patient-derived organoids

Linoy Raz, Haia Khoury, Tal Ben-Yishay…·Uri Ben-David

This study evaluates genomic stability and evolution in cancer patient-derived organoids across 16 cancer types, finding higher genomic fidelity compared to patient-derived xenografts.

DOI 10.64898/2025.12.10.693393

humanwhole-genome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 12, 2026

Chromosomal instability and chromosome 17p loss drive convergentNDE1 synthetic lethality in metastatic cancer cells

Caroline Teddy, Jacob P. Hoj, Julia D. Caci…·Kris C. Wood

The paper identifies NDE1 as a synthetic lethal target in metastatic cancer cells driven by chromosomal instability and Chr17p loss.

DOI 10.64898/2026.02.10.704921

humanwhole-genome sequencing

𝕏 PostBluesky