Author

Cassandra N. Dennys

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Álvaro G. EstéveziD· 1 shared Blaine Russell RobertsiD· 1 shared J. Andres Hernandez· 1 shared Joseph S. BeckmaniD· 1 shared Katherine GanioiD· 1 shared María Clara FrancoiD· 1 shared Peter John CrouchiD· 1 shared Stewart D. Nuttall· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Álvaro G. EstévezORCID

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1 paper

Recent·Most cited

The structure, redox chemistry and motor neuron toxicity of heterodimeric zinc-deficient SOD1-Implications for the toxic gain of function observed in ALS.

Victor A. Streltsov, Katherine Ganio, Stewart D. Nuttall, J. Andres Hernandez, Cassandra N. Dennys, Peter John Crouch, Álvaro G. Estévez, María Clara Franco, Joseph S. Beckman, Blaine Russell Roberts

This study shows that zinc-deficient SOD1 forms toxic heterodimers with wild-type SOD1, contributing to ALS pathology through enhanced redox activity and motor neuron toxicity.

Neurobiology of Disease · Nov 16, 2025Peer-reviewedBiochemistry