Author

María Clara Franco

Florida International UniversityORCID 0000-0002-7971-9805Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Álvaro G. EstéveziD· 1 shared Andrew J. ScottiD· 1 shared Ashish Harish ShahiD· 1 shared Asmita PathakiD· 1 shared Beatriz Mateo-VictorianoiD· 1 shared Blaine Russell RobertsiD· 1 shared Brandon Emanuel LeóniD· 1 shared Bruno ColoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Álvaro G. EstévezORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

γ-aminobutyric acid receptor B signaling drives glioblastoma in females in an immune-dependent manner

Asmita Pathak, Sravya Palavalasa, Bruno Colon, Erika Ciervo, Yadi Zhou, Oriana Teran Pumar, Brandon Emanuel León, Jonathan Mitchell, Pedro Henrique Assenza Tavares Coroa, Beatriz Mateo-Victoriano, Andrew J. Scott, Durga Prasad Gannamedi, Harrison K. A. Wong, Liping Zhang, Juyeun Lee, , Defne Bayık

This study shows GABA receptor B signaling promotes GBM growth in females through immune mechanisms, with sex-specific effects on survival and treatment outcomes.

Nature Cancer · Jun 23, 2026Peer-reviewedCancer Biology

The structure, redox chemistry and motor neuron toxicity of heterodimeric zinc-deficient SOD1-Implications for the toxic gain of function observed in ALS.

Victor A. Streltsov, Katherine Ganio, Stewart D. Nuttall, J. Andres Hernandez, Cassandra N. Dennys, Peter John Crouch, Álvaro G. Estévez, María Clara Franco, Joseph S. Beckman, Blaine Russell Roberts

This study shows that zinc-deficient SOD1 forms toxic heterodimers with wild-type SOD1, contributing to ALS pathology through enhanced redox activity and motor neuron toxicity.

Neurobiology of Disease · Nov 16, 2025Peer-reviewedBiochemistry