Fetally-encoded GDF15 and maternal GDF15 sensitivity are major determinants of nausea and vomiting in human pregnancy
Marlena S. Fejzo, Nuno Rocha, Irène Cimino, SM Lockhart, Catharine D. Petry, RG Kay, Keith Burling, P Barker, AL George, Nirmani Yasara, Anuja Premawardhena, Sungsam Gong, Emma Cook, Kara Rainbow, Dominic J. Withers, , Stephen O’Rahilly
This study identifies fetal and maternal GDF15 as key factors in pregnancy-related nausea and vomiting, showing their roles in disease risk and severity.
bioRxiv · Jun 2, 2023 · PreprintGenetics