Nuclear receptor ligand screening in an iPSC-derived in vitro blood-brain barrier model identifies new contributors to leptin transport
Yajuan Shi, Hyosung Kim, Catherine A. Hamann, Elizabeth M. Rhea, Jonathan M. Brunger, Ethan S. Lippmann
The paper identifies 17β-estradiol and CAT-1 as regulators of leptin transport across an iPSC-derived blood-brain barrier model.
Fluids and Barriers of the CNS · Sep 21, 2022Peer-reviewedNeuroscience