Author

Elizabeth M. Rhea

University of WashingtonORCID 0000-0001-8118-120XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert HungiD· 1 shared Aric Flint LogsdoniD· 1 shared Catherine A. Hamann· 1 shared Chloe A PaolucciiD· 1 shared David A. BakeriD· 1 shared Denys OliinykiD· 1 shared Domenico AcciliiD· 1 shared Elisabeth Zollbrecht· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperPharmacology & Toxicology

Albert HungORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMay 7, 2026

Reprogramming insulin receptor activation with a de novo agonist to overcome severe insulin resistance

Albert Hung, Xinru Wang, Michael Gao…·Eunhee Choi

This study develops a de novo insulin receptor agonist, RF-409, which effectively treats severe insulin resistance in a mouse model by activating a mutant receptor and improving glucose homeostasis.

DOI 10.64898/2026.05.04.722722

mouseproteomics

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NeuroscienceFluids and Barriers of the CNSPeer-reviewedSep 21, 2022

Nuclear receptor ligand screening in an iPSC-derived in vitro blood-brain barrier model identifies new contributors to leptin transport

Yajuan Shi, Hyosung Kim, Catherine A. Hamann…·Ethan S. Lippmann

The paper identifies 17β-estradiol and CAT-1 as regulators of leptin transport across an iPSC-derived blood-brain barrier model.

14 citations

humanbulk RNA-seq

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NeurosciencebioRxivPreprintJul 15, 2020

The S1 protein of SARS-CoV-2 crosses the blood-brain barrier: Kinetics, distribution, mechanisms, and influence of ApoE genotype, sex, and inflammation

Elizabeth M. Rhea, Aric Flint Logsdon, Kim M. Hansen…·Michelle A. Erickson

This study shows that SARS-CoV-2's S1 protein crosses the murine blood-brain barrier via adsorptive transcytosis and is distributed throughout the brain and peripheral tissues.

3 citations

mouseexperimental assay

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