Cell-type-specific whole-genome landscape of ΔFOSB binding in nucleus accumbens after chronic cocaine exposure
Szu-Ying Yeh, Molly S. Estill, Casey K. Lardner, Caleb J. Browne, Angelica M. Minier-Toribio, Rita Futamura, Katherine Beach, Catherine A. McManus, Song‐Jun Xu, Shuo Zhang, Elizabeth A. Heller, Li Shen, Eric J. Nestler
This study maps ΔFOSB binding sites in nucleus accumbens neurons after chronic cocaine exposure using CUT&RUN, revealing enhancer-like regions and interactions with BRG1 and other transcription factors.
bioRxiv · Aug 27, 2022Neuroscience