Protrudin acts at ER-endosome contacts to promote KIF5-mediated endosomal fission and endosome-to-Golgi transport
Julia Kleniuk, Aishwarya G. Nadadhur, Catherine E. Rodger, Emily Wolfenden, Isabelle A. Hall, Samuel R. Cheers, Eliska Zlamalova, Evan Reid
This study identifies protrudin's role in promoting endosomal tubule fission and endosome-to-Golgi transport by interacting with ER-localised VAP proteins and KIF5.
Neurobiology of Disease · Dec 20, 2025Peer-reviewedCell Biology