Characterizing common loss-of-function genes and their potential utility in assessing population variability and chemical susceptibility
CHAN HEE KIM, Zhaohan Zhu, Abderrahmane Tagmount, W. Brad Barbazuk, Rhonda L. Bacher, Leah D. Stuchal, Christopher Joseph Martyniuk, Chris D. Vulpe
The paper identifies common loss-of-function genes and develops a method to integrate them into cell-based models to assess population variability in chemical susceptibility.
bioRxiv · Dec 19, 2025 · PreprintPharmacology & Toxicology