Validation of the association between MRI and gene signatures in facioscapulohumeral dystrophy muscle: implications for clinical trial design
Chao-Jen Wong, Seth D. Friedman, Lauren D. Snider, Sean R. Bennett, Takako Iida Jones, Peter L. Jones, Dennis Shaw, Silvia S. Blemker, Lara Riem, Olivia DuCharme, Richard J.L.F. Lemmers, Silvère M. van der Maarel, Leo H. Wang, Rabi Tawil, Jeffrey M. Statland, Stephen J. Tapscott
The paper validates the association between MRI characteristics and gene signatures in FSHD muscle, supporting their use as biomarkers for clinical trial design.
bioRxiv · Feb 20, 2023 · PreprintMolecular Biology