ImmunologybioRxivPreprint
c-Jun Overexpressing CAR-T Cells are Exhaustion-Resistant and Mediate Enhanced Antitumor Activity
Rachel C. Lynn, Evan W. Weber, David Gennert…·Crystal L. Mackall
This study shows that overexpressing c-Jun in CAR-T cells reduces exhaustion and improves antitumor activity in vivo.
DOI 10.1101/653725