Author

Charles H. D. Williamson

Northern Arizona University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 5 Organism:bacteria (other)· 4 Approach:statistical model· 4 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Jason W. SahliD· 5 shared Adam J. VazqueziD· 3 shared Paul KeimiD· 3 shared Chandler C. RoeiD· 2 shared Amalee E. Nunnally· 1 shared Amy J. VogleriD· 1 shared Andrew SancheziD· 1 shared Brian Thomas FoleyiD· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersGenomics

Jason W. SahlORCID

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Author profile →

5 papers

Recent·Most cited

The historical domestication of a Clostridium botulinum strain used for the industrial production of botulinum neurotoxin

Paul Keim, Roxanne D. Nottingham, Miriam A. Guevara, Ely F. Miller, Amy J. Vogler, Charles H. D. Williamson, Theresa J. Smith, Richard G. Posner, Sabine Pellett, Richard E. Lenski, Jason W. Sahl

This paper reconstructs the genomic evolution of a Clostridium botulinum strain used for industrial botulinum neurotoxin production, identifying key mutations that drove its domestication and adaptation.

bioRxiv · Feb 26, 2026 · PreprintMicrobiology

Bacterial Genome wide association studies (bGWAS) and transcriptomics identifies cryptic antimicrobial resistance mechanisms in Acinetobacter baumannii

Chandler C. Roe, Charles H. D. Williamson, Adam J. Vazquez, Kristen Kyger, Michael Valentine, Jolene R. Bowers, Paul D. Phillips, Veronica Harrison, Elizabeth M. Driebe, David M. Engelthaler, Jason W. Sahl

Frontiers in Public Health · Sep 2, 2020Peer-reviewedGenomics

A global to local genomics analysis of Clostridioides difficile ST1/RT027 identifies cryptic transmission events in a northern Arizona healthcare network

Charles H. D. Williamson, Nathan E. Stone, Amalee E. Nunnally, Heidie Hornstra, David M. Wagner, Chandler C. Roe, Adam J. Vazquez, Nivedita Nandurkar, Jacob Vinocur, Joel Terriquez, John D. Gillece, Jason Travis, Darrin Lemmer, Paul Keim, Jason W. Sahl

This study uses whole genome sequencing to analyze C. difficile isolates and identifies multiple introductions and transmission events in a healthcare network, highlighting genetic variability and antimicrobial resistance.

Microbial Genomics · May 20, 2019Peer-reviewedGenomics

Botulinum-neurotoxin-like sequences identified from an Enterococcus sp. genome assembly

Charles H. D. Williamson, Theresa J. Smith, Brian Thomas Foley, Karen K. Hill, Paul Keim, Jason W. Sahl

The paper identifies a botulinum-neurotoxin-like gene cluster in an Enterococcus sp. genome, similar to known BoNT gene clusters but with unknown pathogenic potential.

bioRxiv · Dec 4, 2017 · PreprintGenomics

Bacterial genome reduction as a result of short read sequence assembly

Charles H. D. Williamson, Andrew Sanchez, Adam J. Vazquez, Joshua Gutman, Jason W. Sahl

The paper simulates short read assemblies of bacterial genomes to assess genome reduction effects and finds up to 25% reduction in some assemblies, correlated with repeat structure.

bioRxiv · Dec 3, 2016 · PreprintGenomics