TEAD switches interacting partners along neural progenitor lineage progression to execute distinct functions
Charles H. Perry, Alfonso Lavado, Venkata Thulabandu, Cody A. Ramirez, Joshua Paré, Rajiv Dixit, Akhilesh Mishra, Jiyuan Yang, Jiyang Yu, Xinwei Cao
The paper shows TEAD1/2 have both YAP/TAZ-dependent and -independent roles in neural progenitor lineage progression, promoting progression by inhibiting Notch and cooperating with INSM1.
Genes & Development · Jul 1, 2025Peer-reviewedDevelopmental Biology