Xinwei Cao

The paper shows that active repression by the TEAD-INSM1 complex maintains neural identity during cerebellum development by preventing muscle fate activation.

The paper shows INSM1 is essential for basal progenitor cell-cycle progression but not their generation, with apical progenitors compensating for reduced neuron production.

The paper shows TEAD1/2 have both YAP/TAZ-dependent and -independent roles in neural progenitor lineage progression, promoting progression by inhibiting Notch and cooperating with INSM1.

This study shows YAP/TAZ are essential for maintaining radial glial cell function during brain development, affecting neuronal and ependymal cell numbers and causing hydrocephaly when disrupted.