Cody A. Ramirez

The paper shows TEAD1/2 have both YAP/TAZ-dependent and -independent roles in neural progenitor lineage progression, promoting progression by inhibiting Notch and cooperating with INSM1.

This study identifies striatal hypercholinergic state and thalamostriatal disruption as causes of amotivation in a 22q11DS mouse model.

The paper identifies 'pliancy genes' in Muller glia that enable rapid response to retinal stress, injury, and disease, showing species-specific differences in their activation between zebrafish and mammals.

The paper presents a single-nucleus transcriptomic atlas of spinal V1 interneurons across development, identifying En1's role in specifying a subset of V1Pou6f2 interneurons and its impact on locomotor output.

This paper demonstrates that thalamocortical assembloids formed from human organoids exhibit functional glutamatergic synapses with short-term plasticity and distinct long-term potentiation and depression mechanisms compared to rodents.

This study identifies high-quality neoantigens in follicular lymphoma patients using WES and RNA-Seq, and initiates a clinical trial of personalized neoantigen vaccines combined with PD-1 blockade.

This study uses ultra-deep exome sequencing to identify recurrent mutations in classical Hodgkin lymphoma HRS cells, demonstrating its utility for analyzing genomic variants in large patient cohorts.

The paper identifies evolutionarily conserved VSX2 enhancer modules in retinal development and shows their functional conservation across species.

The paper predicts MHC anchor positions for 328 HLA alleles and shows that incorporating these improves neoantigen identification by correcting misclassified candidates in tumor samples.

This paper establishes a standard operating procedure for manual refinement of somatic variants in tumor sequencing data to improve consistency and reproducibility.