Chronic intestinal immune activation reveals separable impacts of inflammation and barrier loss on hallmarks of ageing.
Jeanette Alcaraz, Charlotte Keyse, Charles Hall, David W. Walker, David P. Doupé, Rebecca I. Clark
This study shows that intestinal immune activation and barrier loss have distinct effects on microbiota and mortality in Drosophila, independent of each other.
PLoS ONE · Feb 13, 2026Peer-reviewedPhysiology