Author

David P. Doupé

Durham UniversityORCID 0000-0002-9748-9388Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Arthur SmithiD· 1 shared Charles Hall· 1 shared Charlotte Keyse· 1 shared David W. WalkeriD· 1 shared Fanila ShahzadiD· 1 shared Jeanette Alcaraz· 1 shared Laura C. GreavesiD· 1 shared Rebecca I. ClarkiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperDevelopmental Biology

Arthur SmithORCID

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2 papers

Recent·Most cited

The Transcription Factor Sob Maintains Intestinal Stem Cell Homeostasis to Delay Ageing

Fanila Shahzad, Wenbin Wei, Arthur Smith, Laura C. Greaves, David P. Doupé

This study identifies Sob as a transcription factor that maintains intestinal stem cell homeostasis and delays ageing in Drosophila by regulating proliferation and differentiation.

bioRxiv · Jun 2, 2026 · PreprintDevelopmental Biology

Chronic intestinal immune activation reveals separable impacts of inflammation and barrier loss on hallmarks of ageing.

Jeanette Alcaraz, Charlotte Keyse, Charles Hall, David W. Walker, David P. Doupé, Rebecca I. Clark

This study shows that intestinal immune activation and barrier loss have distinct effects on microbiota and mortality in Drosophila, independent of each other.

PLoS ONE · Feb 13, 2026Peer-reviewedPhysiology