Author

Charles Lefranc

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:yeast· 1

Frequent Co-Authors

Anne RoyouiD· 1 shared Derek McCuskeriD· 1 shared Landry PeyraniD· 1 shared Steven P. GygiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

Anne RoyouORCID

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1 paper

Recent·Most cited

A cyclin-polarity feedback network ensures healthy cell proliferation

Landry Peyran, Charles Lefranc, Steven P. Gygi, Anne Royou, Derek McCusker

The paper identifies a feedback mechanism where G1-cyclin-Cdc28Cdk1 corrects polarity errors during cell cycle progression in budding yeast, but can lead to multinucleate cells if defects are irreparable.

Nature Communications · Jun 19, 2026Peer-reviewedCell Biology