Loss of Bicra/Gltscr1 leads to a defect in fetal liver macrophages responsible for erythrocyte maturation in mice.
Surbhi Sood, Aktan Alpsoy, Guanming Jiao, Alisha Dhiman, Charles Samuel King, Gabriella Conjelko, Judy E. Hallett, Sagar M. Utturkar, Jill E. Hutchcroft, Emily C. Dykhuizen
This study shows that Bicra/Gltscr1 knockout mice die perinatally due to defective fetal liver macrophages that impair erythrocyte maturation.
bioRxiv · Oct 17, 2024 · PreprintDevelopmental Biology