Author

Alisha Dhiman

Purdue University West LafayetteORCID 0000-0002-4395-9292Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Emily C. DykhuizeniD· 3 shared Guanming JiaoiD· 3 shared Michael K. WendtiD· 2 shared Sagar M. UtturkariD· 2 shared Aktan AlpsoyiD· 1 shared Aparna B. ShindeiD· 1 shared Brittany L. Allen-PeterseniD· 1 shared Brittany N. HeiliD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMolecular Biology

Emily C. DykhuizenORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular BiologyScience AdvancesPeer-reviewedJul 29, 2026

PBRM1-Dependent PBAF Targeting is Required for EMT and Metastasis in Breast Cancer

Alisha Dhiman, Mitchell G. Ayers, Jamie L McCuiston…·Emily C. Dykhuizen

This study shows that PBRM1 in PBAF is essential for EMT and metastasis in breast cancer by enabling promoter targeting and DNA accessibility for TGFβ1-inducible genes.

1 citation

mousebulk RNA-seq

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Pharmacology & ToxicologybioRxivPreprintMay 29, 2026

Identification, optimization, and structural elucidation of chloroacetamide scaffold as covalent inhibitors for Ubiquitin C-terminal Hydrolase L3

Nagabhushana C. Beeralingappa, Mengyao Lu, Rishi S. Patel…·Daniel Patrick Flaherty

This study identifies and optimizes a chloroacetamide scaffold as a covalent inhibitor for UCHL3, supported by structural and biochemical validation.

DOI 10.64898/2026.05.26.727856

experimental assaydrug response / drug discovery

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Cell BiologybioRxivPreprintMay 6, 2026

PBRM1-VHL cooperation rewires lipid and iron metabolism to promote ferroptosis resistance in clear cell renal cell carcinoma

Guanming Jiao, Luisa F. Baracaldo-Lancheros, Alisha Dhiman…·Emily C. Dykhuizen

This study shows that PBRM1 and VHL cooperate to enhance ferroptosis resistance in ccRCC by modulating lipid and iron metabolism.

DOI 10.64898/2026.05.02.722429

humanbulk RNA-seq

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Developmental BiologybioRxivPreprintOct 17, 2024

Loss of Bicra/Gltscr1 leads to a defect in fetal liver macrophages responsible for erythrocyte maturation in mice.

Surbhi Sood, Aktan Alpsoy, Guanming Jiao…·Emily C. Dykhuizen

This study shows that Bicra/Gltscr1 knockout mice die perinatally due to defective fetal liver macrophages that impair erythrocyte maturation.

1 citation

mouseexperimental assay

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