Le click c'est chic: a plug-and-play virus-like particle vaccination platform enabled by non-canonical amino acid incorporation and click chemistry in the tobacco BY-2 cell-free protein synthesis system
Jorge Armero‐Gimenez, Janis Schleusner, Ruud H. P. Wilbers, A. Schots, Livia Spiga, John S. Tregoning, Ricarda Finnern, Charles Williams
This paper introduces a method to incorporate non-canonical amino acids into proteins using the tobacco BY-2 cell-free system, enabling click chemistry for vaccine development.
bioRxiv · Aug 21, 2025 · PreprintMolecular Biology