Author
Institut universitaire de cardiologie et de pneumologie de Québec
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Yann Grobs, Sarah-Eve S Lemay, Manon Mougin…·Sébastien Bonnet
This study identifies hypusine signaling as a driver of vascular smooth muscle cell proliferation in restenosis and shows that inhibiting DHPS reduces neointimal hyperplasia in preclinical models and human tissue.
Antonella Abi-Sleimen, Ruaa Al‐Qazazi, Yann Grobs…·François Potus
This study develops preclinical models of Group-2 pulmonary hypertension and shows that levosimendan improves cardiac function and reduces pulmonary vascular inflammation and remodeling.
Sarah-Eve S Lemay, Mónica S. Montesinos, Yann Grobs…·Sébastien Bonnet
The study identifies integrin α5β1 as a key driver of pulmonary vascular remodeling in PAH and shows its inhibition improves hemodynamics and RV function in preclinical models.
Yann Grobs, Charlotte Romanet, Sarah-Eve S Lemay…·Sébastien Bonnet
This study identifies ATP-citrate lyase as a driver of vascular remodeling in pulmonary hypertension and coronary artery disease, showing its inhibition can reverse pathological changes.