Author

Charline Jouannet

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Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

David KlatzmanniD· 2 shared Encarnita Mariotti‐FerrandiziD· 2 shared Hélène VantommeiD· 2 shared Kenz Le GougeiD· 2 shared Adrien SixiD· 1 shared Céline AlbalaaiD· 1 shared Gwladys FourcadeiD· 1 shared Johanna DuboisiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

David KlatzmannORCID

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2 papers

Recent·Most cited

Thymic selection of the T cell receptor repertoire is biased toward autoimmunity in females

Hélène Vantomme, Valentin Quiniou, Leslie Adda, Charline Jouannet, Vanessa Mhanna, Céline Albalaa, Pierre Barennes, Nicolas Coatnoan, Vimala Diderot, Johanna Dubois, Gwladys Fourcade, Kenz Le Gouge, Otriv Frédéric Nguekap Tchoumba, Martin Pezous, Paul Stys, , David Klatzmann

The paper identifies sex-specific differences in TCR selection during thymic development, showing female effector T cells have more autoimmunity-associated TCRs while female Tregs have fewer.

eLife · Aug 20, 2026Peer-reviewedSystems Biology

Benchmarking unsupervised methods for inferring TCR specificity

Charline Jouannet, Hélène Vantomme, Kenz Le Gouge, David Klatzmann, Encarnita Mariotti‐Ferrandiz

The paper benchmarks nine unsupervised methods for inferring TCR specificity using a curated database of 190,670 human TCRs, identifying method-specific strengths in retention, purity, and sensitivity.

NAR Genomics and Bioinformatics · Oct 7, 2025Peer-reviewedImmunology