High-purity stem cell-derived β-cells recapitulate key transcriptional and functional features of human islets
Rémi Fiancette, Junyue Huang, Christine Stephens, Jessica Elisabeth Hibbert, George Hewitt, Christopher Carlein, Ali H. Shilleh, Charlotte Clinton, Luana A. Osório, David S. Tourigny, Steven J. Millership, Victoria Salem, David J. Hodson, İldem Akerman
This study develops a scalable method to produce high-purity stem cell-derived β-cells that closely mimic human islets in function and transcriptional profile.
bioRxiv · May 26, 2026 · PreprintCell Biology