İldem Akerman

The paper validates chip-grown vascular tissues as a model for studying vasculature by showing cell provenance affects network formation and transcriptomic profiles.

This study develops a scalable method to produce high-purity stem cell-derived β-cells that closely mimic human islets in function and transcriptional profile.

The paper shows that chromatin folding is organized by recurrent motifs that are reweighted across cell types and states, revealing a structured framework for chromatin variability.

This study sequenced the macronuclear genomes of 22 Tetrahymena thermophila strains to explore intraspecific genomic variation, revealing gene diversification in micronuclear centromeres and a genomic barcode for population dynamics.

The paper shows that a mutation associated with neonatal diabetes disrupts chromatin activation of the insulin gene in human cells.

This study identifies β cell-specific lncRNAs that regulate transcriptional networks and show dysregulation in type 2 diabetes.