Assessment of high-efficacy agonism in synthetic cannabinoid receptor agonists containing l-tert-leucinate
Christopher Lucaj, Soo Jung Oh, Charlotte Pitha, Jordan Davis, Lei Shi, Hideaki Yano
This study identifies structural features of synthetic cannabinoid receptor agonists that confer high-efficacy agonism through bioluminescence resonance energy transfer assays and electrophysiology.
Neuropharmacology · Feb 17, 2026Peer-reviewedPharmacology & Toxicology