Hideaki Yano

The paper maps the anatomical distribution of dopamine D1 and muscarinic M4 receptor-expressing cells across brain regions in mice.

The paper profiles the efficacy of 22 cannabinoid ligands at CB1 and CB2 receptors using BRET assays, finding consistent trends in agonist efficacy and antagonist effects.

This study investigates how LY3154207, a D1R PAM, differentially activates G-protein subtypes and shows it enhances Gs signaling and selectivity of agonists.

The paper compares pharmacological profiles of dimethylindanoylindole isomers at CB1 and CB2 receptors using BRET assays and site-directed mutagenesis.

This study identifies structural features of synthetic cannabinoid receptor agonists that confer high-efficacy agonism through bioluminescence resonance energy transfer assays and electrophysiology.

The paper analyzes bitopic ligands for dopamine D2 and D3 receptors, showing that linker structure and stereochemistry significantly influence transducer bias profiles.