Author

Christopher Lucaj

Northeastern UniversityORCID 0000-0002-9510-0770Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Hideaki YanoiD· 3 shared Soo Jung OhiD· 3 shared Alexander H. WilliamsiD· 1 shared Alexandros MakriyannisiD· 1 shared Chang‐Guo ZhaniD· 1 shared Charlotte Pitha· 1 shared Christos Iliopoulos‐TsoutsouvasiD· 1 shared Gregory B. DudleyiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPharmacology & Toxicology

Hideaki YanoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Efficacy profiling of structurally diverse cannabinoid receptor ligands across transducer-coupling assays

Soo Jung Oh, Christopher Lucaj, Kiera Truong, 郭瑞茹, Hayato Umaoka, Christos Iliopoulos‐Tsoutsouvas, Maria Gerasi, Markos‐Orestis Georgiadis, Lipin Ji, Spyros P. Nikas, Alexandros Makriyannis, Hideaki Yano

The paper profiles the efficacy of 22 cannabinoid ligands at CB1 and CB2 receptors using BRET assays, finding consistent trends in agonist efficacy and antagonist effects.

bioRxiv · Oct 2, 2026 · PreprintPharmacology & Toxicology

Dimethylindanoylindole isomers revealed different pharmacological profiles at CB1 and CB2 cannabinoid receptors

Soo Jung Oh, Ruiru Guo, Christopher Lucaj, Neshira Gutierrez, Kh Tanvir Ahmed, Alexander H. Williams, Chang‐Guo Zhan, Gregory B. Dudley, Hideaki Yano

The paper compares pharmacological profiles of dimethylindanoylindole isomers at CB1 and CB2 receptors using BRET assays and site-directed mutagenesis.

ACS Bio & Med Chem Au · Jul 1, 2026Peer-reviewedPharmacology & Toxicology

Assessment of high-efficacy agonism in synthetic cannabinoid receptor agonists containing l-tert-leucinate

Christopher Lucaj, Soo Jung Oh, Charlotte Pitha, Jordan Davis, Lei Shi, Hideaki Yano

This study identifies structural features of synthetic cannabinoid receptor agonists that confer high-efficacy agonism through bioluminescence resonance energy transfer assays and electrophysiology.

Neuropharmacology · Feb 17, 2026Peer-reviewedPharmacology & Toxicology