Author

Chengrui An

MRC Centre for Regenerative Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Cell Biology· 1 Developmental Biology· 1 Immunology· 1

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Hongwei OuyangiD· 4 shared Bingbing WuiD· 3 shared Kun ZhaoiD· 2 shared Lin Gong· 2 shared XiaoHui Zou· 2 shared Yanshan Liu· 2 shared Yu Li· 2 shared Andrea BaconiD· 1 shared

Activity by Year

2018-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersDevelopmental Biology

Hongwei OuyangORCID

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Author profile →

5 papers

Recent·Most cited

Watch-breaker: establishment of a microwell array-based miniaturized thymic organoid model suitable for high throughput applications.

Viktoria Major, Sam Palmer, Paul Rouse, Jan Morys, Timothy Henderson, Tania Hübscher, Joanna Sweetman, Andrea Bacon, Chengrui An, Guiyun Qiu, Yu Wang, Andrea Corsinotti, Justyna Cholewa-Waclaw, Stephen Jonathan Chapman, Matthias P. Lütolf, , Clare C. Blackburn

The paper introduces a microwell array-based thymic organoid model that supports T-cell development and is suitable for high-throughput analysis.

Cell Reports · Apr 15, 2025Peer-reviewedImmunology

High-resolution architecture of human epiphysis formation

Heng Sun, Ya Wen, Weiliang Wu, Tian Qin, Chengrui An, Chunmei Fan, Yishan Chen, Junfeng Ji, Ting Gang Chew, Jiansong Chen, Hongwei Ouyang

This study maps the differentiation trajectory of human chondrocytes during postnatal finger epiphysis development using single-cell RNA sequencing, revealing new subpopulations and pathways.

bioRxiv · Oct 13, 2020 · PreprintDevelopmental Biology

Diagnosis of Osteoarthritis Subtypes with Blood Biomarkers

Kun Zhao, Junxin Lin, Bingbing Wu, Guofei Sun, Chengrui An, Maswikiti Ewetse Paul, Hongwei Ouyang

The paper identifies two distinct osteoarthritis subtypes using blood gene expression data and develops a classifier to distinguish them with high accuracy.

bioRxiv · Jul 10, 2018 · PreprintBioinformatics

High resolution profile of body wide pathological changes induced by abnormal elastin metabolism in Loxl1 knockout mice

Bingbing Wu, Yu Li, Chengrui An, Deming Jiang, Lin Gong, Yanshan Liu, Yixiao Liu, Jun Li, HongWei Ouyang, XiaoHui Zou

This study uses a new method to profile body-wide transcriptomic changes in Loxl1 knockout mice, revealing systemic immune and proliferative alterations linked to elastin dysfunction and cancer.

bioRxiv · Jun 21, 2018 · PreprintCancer Biology

Cell atlas of human uterus

Bingbing Wu, Yu Li, Yanshan Liu, Kaixiu Jin, Kun Zhao, Chengrui An, Qikai Li, Lin Gong, Wei Zhao, Jinghui Hu, Jianhua Qian, HongWei Ouyang, XiaoHui Zou

This study constructs a single-cell RNA-seq atlas of the human uterus, identifying stem/progenitor-like ciliated epithelial cells and their regulatory signals in endometrial regeneration and disease.

bioRxiv · Feb 19, 2018 · PreprintCell Biology