Arousal increases locus coeruleus blood flow, salience-related brain responses, and modulates negative-valence attentional biases
Andy Jeesu Kim, Chenyang Zhao, Fanhua Guo, Ioannis Pappas, Martin J. Dahl, Heidi I.L. Jacobs, Danny J.J. Wang, Mara Mather
This study shows that arousal increases locus coeruleus blood flow and modulates brain responses to negative-valence stimuli, while the amygdala shows valence-general responses.
bioRxiv · Oct 7, 2025 · PreprintNeuroscience