Mara Mather

In-vivo MRI of noradrenergic and dopaminergic nuclei predicts future cognition and Alzheimers disease progression

The paper uses in-vivo MRI to measure noradrenergic and dopaminergic nuclei integrity in ADNI participants, finding these measures predict future cognitive decline and Alzheimer's progression.

The elusive neural signature of emotion regulation capabilities: evidence from a large-scale consortium

This study examines the relationship between neural activation during reappraisal tasks and individual differences in emotion regulation, finding no shared overlap across three measures and highlighting methodological challenges in fMRI research.

Distinct spatial organization of human hippocampal perfusion and microvascular pulsatility across age

The paper maps human hippocampal perfusion and microvascular pulsatility across age using MRI and integrates these with histological and transcriptomic data, revealing distinct spatial organization and age-related differences.

Effects of different slow paced breathing regimes on cerebrospinal fluid (CSF) oscillations

This study examines how different slow breathing regimes affect cerebrospinal fluid oscillations during wakefulness, finding that infraslow sighing enhances CSF-BOLD coupling.

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

The paper introduces CCSI, a metric linking cortical blood flow and cellular architecture, showing its correlation with metabolic and structural features across brain regions.

Distributed fMRI patterns coupled to low-frequency cardiorespiratory dynamics provide markers of aging

The paper predicts chronological age from whole-brain fMRI-physiology coupling patterns, showing brain regions involved in autonomic regulation are key predictors.

Distinct Neural Systems Supporting Afferent and Efferent Autonomic Activity

The paper investigates brain regions involved in autonomic activity during emotion regulation and rest, finding distinct afferent and efferent systems and age-related differences in their coordination.

Electroencephalography, pupillometry, and behavioral evidence for locus coeruleus-noradrenaline system related tonic hyperactivity in older adults

This study finds that older adults show tonic hyperactivity in the locus coeruleus-noradrenaline system, as evidenced by weaker behavioral, pupillometric, and EEG responses to arousal.

Arousal increases locus coeruleus blood flow, salience-related brain responses, and modulates negative-valence attentional biases

This study shows that arousal increases locus coeruleus blood flow and modulates brain responses to negative-valence stimuli, while the amygdala shows valence-general responses.

Locus coeruleus-related insula activation is associated with implicit learning

This study investigates how noradrenergic systems contribute to implicit learning by combining neuroimaging and behavioral assessments across age groups.

The Physiological Component of the BOLD Signal: Impact of Age and Heart Rate Variability Biofeedback Training

This study examines age-related differences in how cardiac and respiratory fluctuations influence the BOLD signal and shows that HRV-BF training can modulate physiological-BOLD coupling in an age-dependent manner.

Eye movements reveal age differences in how arousal modulates saliency priority but not attention processing speed

This study examines how arousal affects attentional priority and processing speed in young and older adults using eye movements, finding no arousal effect on priority in older adults but increased pupil size and decreased evoked responses.

The integrity of dopaminergic and noradrenergic brain regions is associated with different aspects of late-life memory performance

This study examines the relationship between dopaminergic and noradrenergic brain region integrity and late-life memory performance using longitudinal MRI data.

Associations between locus coeruleus MRI contrast and physiological responses to acute stress in younger and older adults

This study examines the relationship between MRI-measured locus coeruleus structure and physiological stress responses in younger and older adults, finding stronger associations in older adults.

Emotion Down- and Up-Regulation Act on Spatially Distinct Brain Areas:Interoceptive Regions to Calm Down and Other Affective Regions to Amp Up

The paper tests the affective dial hypothesis by comparing brain regions activated during emotion up- and down-regulation, finding they target distinct circuits rather than opposing effects in the same areas.

Age Differences in Diffusivity in the Locus Coeruleus and its Ascending Noradrenergic Tract

The paper examines age-related differences in fractional anisotropy in the locus coeruleus and its ascending noradrenergic tract using diffusion-weighted MRI across three datasets.

Fear in the mind's eye: Mental imagery can generate and regulate acquired differential fear conditioned reactivity

The paper shows mental imagery can generate and regulate differential fear conditioning through visual cortex activation and attention mechanisms.

Behavioral and fMRI evidence that arousal enhances bottom-up attention and memory selectivity in young but not older adults

This study finds that emotional arousal enhances bottom-up attention and memory for salient stimuli in young adults but not older adults, suggesting age-related changes in arousal modulation of selective processing.

Locus coeruleus MRI contrast is associated with cortical thickness in older adults

The paper examines the relationship between locus coeruleus MRI contrast and cortical thickness in older and younger adults, finding a positive association in specific brain regions.

Noradrenergic responsiveness supports selective attention across the adult life span

This study investigates age-related differences in noradrenergic system responsiveness and its association with attentional performance in younger and older adults using pupillometry and EEG.

Isometric exercise facilitates attention to salient events in women via the noradrenergic system

This study shows that isometric handgrip increases attentional performance and LC-frontoparietal connectivity in women, suggesting a link between noradrenergic activity and attention.

Higher rostral locus coeruleus integrity is associated with better memory performance in older adults