GenomicsCirculationPeer-reviewed
Gene neighbourhood integrity disrupted by CTCF loss in vivo
Dominic Paul Lee, Wilson Lek Wen Tan, Chukwuemeka George Anene-Nzelu…·Roger Foo
This study shows that loss of CTCF in mouse cardiomyocytes disrupts gene neighbourhoods, leading to ectopic enhancer-promoter interactions and heart failure.