Author

Jianming Jiang

National University of SingaporeORCID 0000-0003-3251-2716Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Amanda C. GarfinkeliD· 1 shared Angela C. Tai· 1 shared Barbara A. McDonoughiD· 1 shared Chang Jie Mick LeeiD· 1 shared Charles S RedwoodiD· 1 shared Cheryl Xueli Chan· 1 shared Christine E. SeidmaniD· 1 shared Christopher N. ToepferiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Amanda C. GarfinkelORCID

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2 papers

Recent·Most cited

GenomicsCirculationPeer-reviewedFeb 5, 2019

Gene neighbourhood integrity disrupted by CTCF loss in vivo

Dominic Paul Lee, Wilson Lek Wen Tan, Chukwuemeka George Anene-Nzelu…·Roger Foo

This study shows that loss of CTCF in mouse cardiomyocytes disrupts gene neighbourhoods, leading to ectopic enhancer-promoter interactions and heart failure.

60 citations

mouseChIP-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintApr 18, 2018

MYBPC3 Mutations cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy

Christopher N. Toepfer, Hiroko Wakimoto, Amanda C. Garfinkel…·Christine E. Seidman

The paper shows that MYBPC3 mutations disrupt myosin relaxation states, leading to hyper-contractility in HCM, and that targeting myosin can alleviate these effects.

2 citations

humanmouse

𝕏 PostBluesky