Author

Chia‐Lun Tsai

Massachusetts General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:zebrafish· 1

Frequent Co-Authors

Hyunho LeeiD· 1 shared J. Keith JoungiD· 1 shared Jing-Ruey Joanna YehiD· 1 shared Junyan Ma· 1 shared Karl PetriiD· 1 shared Weiting Zhang· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperGenomics

Hyunho LeeORCID

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1 paper

Recent·Most cited

GenomicseLifePeer-reviewedJun 7, 2024

Enhancing CRISPR prime editing by reducing misfolded pegRNA interactions

Weiting Zhang, Karl Petri, Junyan Ma…·Jing-Ruey Joanna Yeh

This study identifies pegRNA misfolding as a factor limiting CRISPR prime editing efficiency and shows refolding and point mutations can significantly improve it in zebrafish embryos.

24 citations

zebrafishexperimental assay

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