Structurally targeted mutagenesis identifies key residues supporting α-synuclein misfolding in multiple system atrophy
Patricia M. Reis, Sara A. M. Holec, Chimere Ezeiruaku, Matthew P. Frost, Christine K. Brown, Samantha L Liu, Steven H. Olson, Amanda L. Woerman
The paper identifies key residues in α-synuclein that support misfolding in multiple system atrophy using mutagenesis and computational modeling.
Journal of Parkinson s Disease · Oct 17, 2024Peer-reviewedNeuroscience