BiochemistryScientific ReportsPeer-reviewed
Use of phase plate cryo-EM reveals conformation diversity of therapeutic IgG with 50 kDa Fab fragment resolved below 6 angstrom
Hsin-Hung Lin, Chun-Hsiung Wang, Shih-Hsin Huang…·Wei‐Hau Chang
This study uses phase plate cryo-EM to reveal conformational diversity in therapeutic IgG, achieving sub-nanometer resolution of the Fab fragment.