Kazuyoshi Murata

Eukaryotes' closest relatives are internally simple syntrophic archaea

This study isolates two Hodarchaeales strains, closely related to the eukaryotic common ancestor, revealing their syntrophic, anaerobic, and oxygen-tolerant physiology and genomic features.

MC-Bayes: A Python-based wrapper for MotionCor3 processing of EER files compatible with Bayesian polishing

MC-Bayes provides a Python wrapper for MotionCor3 to process EER files for Bayesian polishing, enabling faster motion correction on GPU systems compared to CPU-based methods.

Conformational plasticity of the human norovirus GII.3 capsid reveals alternative P domain interaction networks

This study identifies two distinct capsid conformations in human norovirus GII.3 virus-like particles, revealing conformational switching and alternative P domain interaction networks.

Integrative structural interactomics reveals protein organization and structure in a giant virus

The paper integrates structural and proteomic methods to characterize the protein organization of a giant virus, identifying sub-compartments and membrane protein topologies.

Near-atomic structures of human astrovirus capsids reveal a subunit-specific maturation mechanism

The paper reports near-atomic cryo-EM structures of human astrovirus serotype 4 in immature and mature states, revealing a subunit-specific maturation mechanism driven by protease accessibility.

Structural basis for Ca2+-dependent allosteric modulation of cardiac ryanodine receptor by Ryanozole

This study defines the mechanism of Ryanozole's Ca2+-dependent modulation of RyR2 using cryo-EM, mutagenesis, and functional assays, revealing its structural basis for CPVT therapy.

Key role of P230 in the hinge region on the IgG architecture and function

This study investigates the role of Pro230 in the hinge region of IgG by deleting it, revealing structural changes and functional effects on FcγRI-mediated activity.

Endoplasmic reticulum patterns insect cuticle nanostructure

The paper reveals how the endoplasmic reticulum (ER) is repurposed via autophagy to form nanopores in Drosophila olfactory organs, controlled by the Gox protein.

Characterization of an enigmatic tubular ultrastructure in the bacterial defensive symbiont of the Asian citrus psyllid

This study characterizes a unique tubular structure in the bacterial symbiont of the Asian citrus psyllid, revealing its structural features and potential role in mechanical stability and protein synthesis.

Nanoscale visualization of Drosophila E-cadherin ectodomain fragments and their interactions using DNA origami nanoblocks

This paper uses DNA origami nanoblocks to visualize DE-cadherin ectodomain interactions and reveal a hinge-like structure involved in mechanical flexibility and adhesion-like processes.

Subnanometer structure of medusavirus capsid during maturation using cryo-electron microscopy

The paper uses cryo-EM to reveal structural changes in medusavirus capsids during maturation, identifying dynamic rearrangements of minor capsid proteins and penton proteins.

Six states of Enterococcus hirae V-type ATPase reveals non-uniform rotor rotation during turnover

The paper identifies six states of Enterococcus hirae V-ATPase using cryo-EM, revealing non-uniform rotor rotation during turnover.

Sub-3 A resolution structure of apoferritin using a multi-purpose TEM with a side-entry cryo-holder

This study demonstrates that a multi-purpose TEM with a side-entry cryo-holder can achieve high-resolution cryo-EM single particle analysis, as shown by a 3 Å resolution map of apoferritin.