Keiichi Namba

The paper characterizes pseudaminic acid modifications on the lateral flagellar filament of Vibrio alginolyticus and shows Maf is required for filament formation.

This study shows thermal fluctuations help bacterial flagellar motors rotate quickly at low load by compensating for limited power stroke reach.

The paper expresses MreB isoforms from Haloplasma in a synthetic bacterium to study motility, finding distinct movement patterns and force directions.

The paper reports the cryo-EM structure of CYP2C9, revealing a dimer-of-trimers assembly and its stabilization mechanisms.

This study identifies and characterizes FoeAB, a type IV ABC transporter in Streptococcus pneumoniae that exports fosfomycin, using functional assays and cryo-EM structures.

This study edits the chloroplast genome of Arabidopsis thaliana to enhance Rubisco catalytic efficiency, improving photosynthesis and plant growth without reducing Rubisco content.

The paper determines the structure of an active FlhA ring and shows how it couples substrate specificity to export engine activation through linker-mediated docking.

This study identifies a conserved residue in FlhA that couples export gate activation to substrate specificity switching in bacterial flagellar assembly.

This study reveals the structural mechanism of MyD88 oligomerization in innate immune signaling using cryo-EM and high-speed AFM.

The paper shows that removal of inhibitory components Fluke and FlhBCCD by FliK drives the flagellar T3S specificity switch from early to late secretion.

This study identifies a dual regulatory mechanism for a CoA transferase in Thermus thermophilus, controlled by NAD+-sensing and acetylation, which fine-tunes β-oxidation flux based on cellular metabolic states.

The paper converts an agonistic anti-TNFR2 biparatopic antibody into an antagonist by inserting peptide linkers into the hinge region, altering its immunocomplex formation.

This study reports the cryo-EM structure of the ZapA-FtsZ complex, revealing how ZapA interacts with FtsZ to regulate bacterial cell division.

The paper presents a 3.2 Å resolution cryo-EM structure of a dimeric F1-like ATPase complex in Mycoplasma mobile, revealing its role in gliding motility through conserved rotary mechanisms.

The paper presents a cryoEM structure of the FliPQR complex in closed form, revealing how FliE opens the periplasmic gate for flagellar rod assembly.

This paper reports cryoEM structures of the flagellar MS-ring and identifies how FliF subunits adopt different conformations to generate three rotational symmetries.

This study reveals a pH-induced conformational switching mechanism in Betanodavirus protrusions that governs infectivity through dynamic structural changes.

This study uses phase plate cryo-EM to reveal conformational diversity in therapeutic IgG, achieving sub-nanometer resolution of the Fab fragment.

This study identifies the role of FlhA's GYXLI motif and the flagellar ATPase complex in regulating substrate specificity switching of the fT3SS during flagellar assembly in Salmonella.

The paper reports the cryo-EM structure of a bacterial adhesin complex and identifies epitopes that affect adhesion and motility in Mycoplasma pneumoniae.

The paper presents the high-resolution structure of a microtubule-like tube formed by FtsZ-monobody complexes, revealing structural similarities to microtubules and the role of FtsZ protofilament plasticity.

The paper introduces an epoxidized graphene grid (EG-grid) that improves particle density and orientation in cryoEM, enabling high-resolution structural analysis with fewer micrographs.

The paper presents nine alpaca nanobodies that recognize conserved hidden epitopes on SARS-CoV-2 spike proteins across variants and maintain neutralizing activity against escape mutations.

The paper reports the structure of the LP ring of the bacterial flagellar motor using electron cryomicroscopy, revealing its 26-fold symmetry and intersubunit interactions.